RV521 CAS No.: 1903763-82-5

RV521(Sisunatovir)

Catalog No.: URK-V607  Only Used For Lab.

RV521 (Sisunatovir) is a potent, orally active, small-molecule inhibitor of RSV fusion, demonstrates potent antiviral activity across multiple strains of RSV in vitro..

 

Biological Activity

RV521 (Sisunatovir) is a potent, orally active, small-molecule inhibitor of RSV fusion, demonstrates potent antiviral activity across multiple strains of RSV in vitro.

 

Physicochemical Properties

M.Wt	446.45
Formula	C23H22F4N4O
CAS No.	1903763-82-5
Storage	Solide Powder -20 °C 3years; 4°C 2years	In Solvent -80°C 6 Months -20°C 1 Months
Solubility	10 mM in DMSO
Chemical Name	1'-((5-(aminomethyl)-1-(4,4,4-trifluorobutyl)-1H-benzo[d]imidazol-2-yl)methyl)-6'-fluorospiro[cyclopropane-1,3'-indolin]-2'-one

 

References

1. Yu-Ki Tahara, et al. J Am Chem Soc. 2018 Feb 14;140(6):2105-2114.

2. Qin S, et al. J Immunol. 2020 Oct 15;205(8):2231-2242.

3. Zhang L, et al. Redox Biol. 2021 Apr;40:101848.

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